In its analyst event presentation, Roche reported that it intends to initiate three studies with trastuzumab emtansine for early stage HER2-positive breast cancer, assessing the compound:
Roche expects to begin all three trials in 2013. Additional details on the plans reported are available on Roche's website, www.roche.com.
"Genentech and Roche have unparalleled experience in the development of HER2-targeting antibody therapies for breast cancer," commented
Trastuzumab emtansine is currently being evaluated in three Phase III trials for the treatment of HER2-positive metastatic breast cancer. Data from the first of these, EMILIA, were reported in a plenary session at ASCO earlier today and, per Roche, will form the basis of its applying for marketing approval of the compound in the US and
Trastuzumab emtansine comprises ImmunoGen's DM1 cancer cell-killing agent linked using the Company's method of attachment to the trastuzumab antibody developed by
About
This press release includes forward-looking statements. For these statements, ImmunoGen claims the protection of the safe harbor for forward-looking statements provided by the Private Securities Litigation Reform Act of 1995. It should be noted that there are risks and uncertainties related to the development of novel anticancer products, including trastuzumab emtansine, including risks related to clinical studies and regulatory submissions, their timings and results. A review of these risks can be found in ImmunoGen's Annual Report on Form 10-K for the fiscal year ended
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